VThunter
a database for single-cell screening of virus target cells in animal kingdom
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Drosophila

Scientific Name: Drosophila melanogaster

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Protostomia-> Ecdysozoa-> Panarthropoda-> Arthropoda-> Mandibulata-> Pancrustacea-> Hexapoda-> Insecta-> Dicondylia-> Pterygota-> Neoptera-> Endopterygota-> Diptera-> Brachycera-> Muscomorpha-> Eremoneura-> Cyclorrhapha-> Schizophora-> Acalyptratae-> Ephydroidea-> Drosophilidae-> Drosophilinae-> Drosophilini-> Drosophila-> Sophophora-> melanogaster group-> melanogaster subgroup

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Varicella Zoster Virus

Family: Herpesviridae

Receptor: IDE

Receptor IDE information

Summary: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_1007 2017.12 Smart-seq2 Brain Normal 1842 Link
Vthunter_1012 2018.09 Drop-seq EyeDisc Normal 6200 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of IDE in human tissues   [NCBI]

Expression: Ubiquitous expression in skin (RPKM 17.4), testis (RPKM 9.9) and 25 other tissues

Protein expression of IDE in human tissues   [Proteinatlas]